TAG does not offer authentication and encapsulation services for cards with in-person autographs, and can only grade and encapsulate eligible cards with autographs which have been certified by the manufacturer.
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Additionally, TAG cannot accept in-person signed cards which have been previously authenticated by PSA / DNA, Beckett, CGC, or JSA for encapsulation.
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TAG does not authenticate in-person signatures but also cannot ignore the presence of an added signature on a card and authenticate and grade the trading card regardless as this could easily create confusion as to which aspect of the collectible TAG had approved and authenticated as genuine.
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TAG's current eligibility guidelines are kept up-to-date at https://help.taggrading.com/en/articles/6712887-what-can-i-grade-with-tag